Arthur S. Edison, Associate Professor at Biochemistry UF

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Arthur S. Edison

Associate Professor

Ph.D., University of Wisconsin-Madison, 1993

Research

NMR, Structural Biology & Neurochemistry

Office:

LG-187 B

Lab:

LG-150 B

Telephone:

(352) 392-4535

Email:

art@mbi.ufl.edu

Home Page:

http:// edison.mbi.ufl.edu/

BIOGRAPHY
Arthur S. Edison completed his Ph.D. in biophysics from the University of Wisconsin-Madison where he developed and applied NMR methods for protein structural studies under the supervision of John Markley and Frank Weinhold. In 1993, Dr. Edison joined the laboratory of Anthony O. W. Stretton at the University of Wisconsin as a Jane Coffin Childs postdoctoral fellow where he investigated the role of neuropeptides in the nervous system of the parasitic nematode Ascaris suum. He joined the faculty at the University of Florida in 1996. Dr. Edison is the recipient of the 1997 American Heart Association Robert J. Boucek Award and of a CAREER Award from the National Science Foundation in 1999.
RESEARCH DESCRIPTION
My laboratory focuses on the structural and functional characterization of signaling peptides and proteins known to function without a well-defined folded structure. These molecules typically do not crystallize, but can be characterized by NMR spectroscopy and computational approaches. We are discovering that biological function is often associated with a change in both structure and flexibility. Most of our research involves NMR spectroscopy, computational biology and molecular biology. On-going projects focus on: neuropeptides and their precursor proteins; a protein inhibitor of yeast proteinase A; MARCKS, the major hippocampal substrate for PKC phosphorylation; mutacin 1140, a potent antibiotic; neuropeptide agonists and antagonists of melanocortin receptors.