Linda B. Bloom, Associate Professor at Biochemistry UF

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Linda B. Bloom

Associate Professor

Ph.D., University of Florida,

Research

DNA Replication & Repair

Office:

R3-165 A

Lab:

R3-149 A

Telephone:

(352)392-8708

Email:

lbloom@ufl.edu

Home Page:

http:// homepage.mac.com/lbbloom/bloomlab/bloomlabindex.html

BIOGRAPHY
Associate Professor Linda B. Bloom earned her Ph.D. degree in organic chemistry from the University of Florida for her work on anabaseine. She joined Myron Goodman's laboratory at the University of Southern California in 1990 where she used novel florescent techniques to study DNA replication. From 1996-1999, Dr. Bloom was an Assistant Professor of Chemistry and Biochemistry at Arizona State University. She joined the faculty in the Department of Biochemistry and Molecular Biology at the University of Florida in 1999.
RESEARCH DESCRIPTION
Our general research interests are in enzyme catalyzed reactions and in dynamic protein-protein and protein-DNA interactions that are required for DNA replication and repair. Our major research objectives are to characterize the biochemical mechanisms of individual enzymes required for DNA replication and repair, and to characterize the coordination and timing of the interactions between these proteins. Currently, we are working on two major research projects. The first, in the area of DNA replication, is focused on the mechanism of assembly of multi-protein replication complexes on DNA. The second, in the area of DNA repair, is focused on the mechanism by which DNA glycosylases identify and excise damaged DNA bases to initiate the base excision repair pathway.